翁经纬，化学系助理研究员，1983年出生。2005年毕业于复旦大学化学系，2010年于复旦大学物理化学专业获博士学位，师从王文宁教授。而后在复旦大学生物医学研究院进行博士后研究，师从杨芃原教授。2012年8月进入复旦大学化学系，化学生物学专业，任职讲师。2018年8月起任助理研究员。目前已发表SCI论文30余篇，曾在Angewandte Chemie-International Edition, Journal of the American Chemical Society, Chemical Science等著名期刊上发表论文。
主要研究方向：自组装机理和调控机制，内在无序蛋白质构象系综和动力学，膜蛋白底物转运机制等。
电子邮件：jwweng@fudan.edu.cn
近五年发表的论文：
1. JW Weng+, MH Yang+, WN Wang*, X Xu* & ZQ Tian. Revealing Thermodynamics and Kinetics of Lipid Self-Assembly by Markov State Model Analysis. Journal of the American Chemical Society, 2020, 142(51), 21344.
2. DD Wang, JW Weng* & WN Wang*. Glycerol transport through the aquaglyceroporin GlpF bridging dynamics and kinetics with atomic simulation. Chemical Science, 2019, 10, 6957.
3. SW Wu, DD Wang, J Liu, YT Feng, JW Weng*, Y Li, X Gao, JW Liu* & WN Wang*. The Dynamic Multisite Interactions between Two Intrinsically Disordered Proteins. Angewandte Chemie-International Edition, 2017, 56(26), 7515.
4. JW Weng and WN Wang*. Dynamic multivalent interactions of intrinsically disordered proteins. Current Opinion in Structural Biology, 2020, 62, 9-13.
5. MH Yang, YG Tang, JW Weng*, ZJ Liu* & WN Wang*. The Role of Calcium in Regulating the Conformational Dynamics of d-Galactose/d-Glucose-Binding Protein Revealed by Markov State Model Analysis. Journal of Chemical Information and Modeling, 2021, accepted (acs.jcim.0c01119).
6. D Chen+, JW Weng+, TH Shen & X Xin*. The enhanced extended phenomenological kinetics method to deal with timescale disparity problem among different reaction pathways. Journal of Computational Chemistry, 2020, 41, 2115.
7. JW Weng & WN Wang*. Structural Features and Energetics of the Periplasmic Entrance Opening of the Outer Membrane Channel TolC Revealed by Molecular Dynamics Simulation and Markov State Model Analysis. Journal of Chemical Information and Modeling, 2019, 59, 2359.
8. DD Wang, JW Weng* & WN Wang*. An Unconventional Ligand-Binding Mechanism of Substrate-Binding Proteins: MD simulation and Markov State Model Analysis of BtuF. Journal of Computational Chemistry, 2019, 40(14), 1440.
9. JW Weng+, S Gu+, X Gao, XH Huang* & WN Wang*.(共一作) Maltose-binding protein effectively stabilizes the partially closed conformation of the ATP-binding cassette transporter MalFGK(2). Physical Chemistry Chemical Physics, 2017, 19(14), 9366. IF = 4.1.
10. ZC Zuo, JW Weng* & WN Wang*. Insights into the Inhibitory Mechanism of D13-9001 to the Multidrug Transporter AcrB through Molecular Dynamics Simulations. Journal of Physical Chemistry B, 2016, 120(9), 2145-2154. IF = 3.2.
11. C Pan, JW Weng* & WN Wang*. The Conformational Dynamics and Protein-Substrate Interaction of ABC Transporter BtuCD at the Occluded State Revealed by Molecular Dynamics Simulations. Biochemistry, 2016, 55(49), 6897.
12. C Pan, JW Weng* & WN Wang*. ATP Hydrolysis Induced Conformational Changes in the Vitamin B12 Transporter BtuCD Revealed by MD Simulations. Plos One, 2016, 11(11), e0166980.
